Start the Lab From the Beggining Again

Starting a LaboratoryStarting a new lab is an exciting venture, full of promise, creativity, and new discoveries. Information technology'south also not the easiest affair to accomplish. Considerable deliberation goes into starting a lab, including mountains of paperwork and countless decisions that you need to make. Hither are some factors to consider when starting a laboratory that can help it become more than productive, efficient, and to a higher place all, successful.

#1 – Organization

The first decision whatever new lab should brand is how to organize its workflow, inventory, notebooks, and result analysis. A articulate-cutting arrangement is essential to implement as early as possible because switching systems later may necessitate additional time and homo resources the lab cannot necessarily afford. The main objective here is to choose a system suited to your research's proposed needs. Several software types can serve equally organizational systems, including a laboratory information direction organisation (LIMS), which tin manage workflow, inventory, and clarify results, ofttimes through a secure deject-based system. Y'all can also use electronic notebooks to continue detailed lab notes in place of classical handwritten notebooks while integrating seamlessly into most LIMS every bit well. Combining a LIMS with an electronic notebook provides a much more consistent process than traditional lab notebooks, as each pace is verified by scanning barcodes or radio-frequency identification (RFID).

#2 – Lab Infinite

The space available for your enquiry may depend on whether yous're inheriting space in an institution or designing a new lab from scratch. Regardless of your state of affairs, it's necessary to assess what workflow might look similar in the long-term before planning. Ideally, y'all should design your lab infinite to optimize efficiency and promote collaboration between areas that demand it. Open lab concepts are an excellent way to encourage the sharing of both ideas and equipment. However, for the design to optimize efficiency, it must also maximize the space available and answer to your staff's needs.

#3 – Safe

When evaluating lab space, workflow, and protocols, take the time to identify potential hazards and safety problems immediately. The last matter anyone would desire is a premature piece of work stoppage because a hazard went unaccounted for or, in the worst example, because an accident has occurred. Ensuring anybody is set up for mandatory safety training is necessary, every bit is making sure y'all outfit your lab with the basics, like a burn extinguisher, burn blankets, a first-assistance kit, and emergency showers.

#iv – Equipment

Major equipment purchases volition undoubtedly vary from lab to lab, depending on inquiry needs. Still, it's also useful to collaborate with others and identify things like confocal microscopes and other specialized equipment shared beyond labs. When it comes to the essentials, information technology'south worth covering as many bases as you tin, fifty-fifty if there isn't an immediate demand. Here is a list of many of the basics all labs should purchase, segmented co-ordinate to a specific demand, including:

Cell culture: Laminar flow hood, CO2 incubators, microscope with camera, tabletop cooling centrifuge, mini centrifuge for 1.5 to 2 ml vials, water bath, vacuum suction to aspirate media, cell counter, liquid nitrogen Dewars, cell freezing container, Petri dishes and/or flasks, and cryo vials with cryogenic labels.

Biochemistry and molecular biological science: SDS-Folio minipreps, western blot transfer apparatus, PCR and/or qPCR thermocyclers, sonicator, agarose gel apparatus, power supply, DNA/RNA gel imager, Nanodrop or other methods of measuring Dna/RNA concentration, tissue homogenizer, plate reader, pH meter, heat block, vortex, heat block, rotating shaker, centrifuges (for 50 ml tubes, microplates, one.5-2 ml tubes, and an ultracentrifuge).

General equipment: Pipettes, tips, tubes, racks, timers, scissors, glassware, stir confined, cylinders, Bunsen burner, fridges and freezers (4°C, -20°C, -80°C), residue, gloves, carboys, figurer, autoclave bin, tapes, labels, printers, and markers.

#5 – Advice

While some facets of advice can be toggled via general lab arrangement (for instance, booking equipment can be taken care of by electronic cloud-based systems), information technology's essential to relay responsibilities effectively and to communicate results to the members of your lab. Making a weekly schedule for all new employees that includes either one-on-ane or group lab meetings is the nigh apparent solution to troubleshooting problems, many of which will most likely occur right from the outset.

Information technology'due south as well worth evaluating all other advice channels, from creating a website for your lab that can communicate new inquiry findings and task positions to decide the best way to reach your lab members in an emergency. Even social media etiquette should be addressed, with rules for conduct and disclosure of potentially confidential information. The advice construction should exist set from the very offset, so there are fewer misunderstandings later.

#6 – Culture

The people who work in your lab are the ones who volition ultimately determine on the quality and quantity of work that's published. Establishing and communicating clear expectations early volition set the tone when interviewing new staff, providing a solid framework that keeps members motivated and accountable.

Accountability can likewise be maintained past adhering to the Swiss Cheese model of fault management, which stresses that errors are primarily due to lapses in the system itself, without placing the blame squarely at the human foot of personnel conducting the testing. In this model, if errors occur, information technology's a matter of introducing new protocols or reconfiguring the organization itself to help reduce errors and increment productivity.

In keeping with the Swiss Cheese model, flexibility and openness are major assets to purvey in any new lab. It's important to bestow empathy to those you're working with, fifty-fifty if it's just an undergraduate working office-time in your lab—remember, you lot were likely in the same situation as those working for you lot now—and to provide both constructive criticism and positive feedback.

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Source: https://blog.labtag.com/6-factors-to-consider-when-starting-a-laboratory/

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